Abstract Background IL-10 knockout (KO) mice are protected from experimental autoimmune encephalomyelitis (EAE) with low-dose estrogen (E2) treatment similar to wild-type (WT) mice. Previous studies have demonstrated a decrease in tumor necrosis factor in all E2-treated groups. which led to the protection of the mice. Methods This study used IL-10 KO mice and WT mice treated either wi... https://www.opheliasmuse.com/