Opioid-induced hyperalgesia (OIH) happens when opioid analgesic paradoxically will cause increase in discomfort, or increase in sensitivity to pain; this situation differs from tolerance, that's the necessity for increasing doses of opioids to take care of a defined result Conversion from other opioids: Start Exalgo dose at 50% of calculated https://ammone210odt7.elbloglibre.com/profile